Electrochemical behaviour of amodiaquine detection using boron doped diamond electrodes

In this study, we propose a simple and low-cost procedure by using boron-doped diamond (BDD) as a working electrode to detect amodiaquine (AQ) in phosphate buffer solution (PBS) and potassium perchlorate (KClO 4 ) electrolytes. We used cyclic voltammetry (CV) and different pulse voltammetry (DPV) techniques. By using DPV, oxidation of AQ in PBS and KClO4 was observed at +0.28 V and +0.4 V ( vs. Ag/AgCl), respectively. To investigate the redox reaction mechanism, the pH and scan rate were varied. A linear calibration curve was observed in the concentration range of 0.0645 – 0.3 µM with a detection limit of 1.47×10 -3 µM (S/N=3) for PBS and 4.81×10 -3 µM (S/N=3) for KClO 4 . This result confirms that BDD electrodes could potentially be used to detect AQ.