Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network

In line with previous studies, our data suggest that DMT does not ameliorate disability worsening in PPMS, in general. However, we observed a beneficial effect of DMT on disability worsening in patients with aggressive predicted disability trajectories.

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Publication Details

Journal
Journal of Neurology Neurosurgery & Psychiatry
Published
2024-12-06
DOI
https://doi.org/10.1136/jnnp-2024-334700
Citations
1
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.42

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article

Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network

Melinda Magyari, Tim Spelman, Jonathan Ciron, Pierre Labauge et al.
1 citations
Journal of Neurology Neurosurgery & Psychiatry
Multiple Sclerosis Research Studies
0.42
article

Disease-modifying treatment and disability progression in subclasses of patients with primary progressive MS: results from the Big MS Data Network

Melinda Magyari, Tim Spelman, Jonathan Ciron, Pierre Labauge, Jerome De Seze, José Luis Sánchez-Menoyo, María Trojano, Nils Koch‐Henriksen, Sandra Vukusic, Tomáš Kalinčík, Katherine Buzzard, Dana Horáková, Helmut Butzkueven, Alessio Signori, Élisabeth Maillart, Johannes Lorscheider, Aurélie Ruet, Frederik Elberling, Anneke van der Walt, Sara Eichau, Jens Kühle, Julie Prévost, Izanne Roos, Jan Hillert, Guillaume Mathey, Luigi Pontieri, Hélène Zéphir, Pierre Grammond, Robert Hyde, Per Soelberg Sørensen, Cristina Ramo‐Tello, Alexandre Prat, Oliver Gerlach, Pascal Benkert, Laure Michel, Suvitha Subramaniam, Orla Gray, Raed Alroughani, Marc Girard, Arnaud Kwiatkowski, Anna Glaser, Jeanette Lechner Scott
article en
1 citations

Abstract

In line with previous studies, our data suggest that DMT does not ameliorate disability worsening in PPMS, in general. However, we observed a beneficial effect of DMT on disability worsening in patients with aggressive predicted disability trajectories.

Journal of Neurology Neurosurgery & PsychiatryVol. 96(6)
Université Claude Bernard Lyon 1 (FR), University of Copenhagen (DK), The Royal Melbourne Hospital (AU), Box Hill Hospital (AU), Université de Bordeaux (FR), The University of Melbourne (AU), University of Basel (CH), Université de Montpellier (FR), Charles University (CZ), Université de Lille (FR), John Hunter Hospital (AU), The Alfred Hospital (AU), Glostrup Hospital (DK), Aarhus University Hospital (DK), University Hospital of Basel (CH), Copenhagen University Hospital (DK), Rigshospitalet (DK), Amiri Hospital (KW), Karolinska Institutet (SE), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Lille (FR), Centre Hospitalier Universitaire de Toulouse (FR), Maastricht University (NL), Sorbonne Université (FR), Hunter Medical Research Institute (AU), Hospital Universitario Virgen Macarena (ES), Cégep de Lévis (CA), Centre de Recherche en Neurosciences de Lyon (FR), Assistance Publique – Hôpitaux de Paris (FR), Eastern Health (AU), Hospices Civils de Lyon (FR), Observatoire Français de la Sclérose en Plaques (FR), Hôpital Notre-Dame (CA), Hospital de Galdakao (ES), Pitié-Salpêtrière Hospital (FR), Neurocentre Magendie (FR), Zuyderland Medisch Centrum (NL), Danish Multiple Sclerosis Center (DK), Centre Intégré de Santé et de Services Sociaux des Laurentides (CA), Hospital Universitari Germans Trias i Pujol (ES), Hunter New England Local Health District (AU), Centre Hospitalier Universitaire de Rennes (FR), Hôpital Saint-Vincent-de-Paul (FR), South Eastern Health and Social Care Trust (GB), University of Bari Aldo Moro (IT), Monash University (AU), Université de Strasbourg (FR), Université de Montréal (CA), University of Genoa (IT), Université de Lorraine (FR)
Biogen, Agence Nationale de la Recherche
Openalex Percentile: Top 32%
Multiple Sclerosis Research Studies
0.42
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