Comparison of the efficacy of curcumin and its nano formulation on dexamethasone-induced hepatic steatosis, dyslipidemia, and hyperglycemia in Wistar rats
This study demonstrates that curcumin NPs has a superior effect on reducing oxidative stress and improving metabolic parameters in diabetes compared to curcumin. by enhancing the bioavailability and stability of curcumin, the nanoformulation showed stronger therapeutic potential for managing high blood sugar, cholesterol issues, and liver health, positioning curcumin NPs as a promising alternative to conventional treatments for diabetes and its complications.
Authors
- Amany M. Hamed (ORCID: https://orcid.org/0000-0002-5995-8358)
- Azza Ma Abouelella
- Islam Ragab (ORCID: https://orcid.org/0000-0002-5271-5441)
- Ahmed Hamed (ORCID: https://orcid.org/0000-0003-2923-7012)
- Ahmed Osman
- Dalia A Elbahy
- Shymaa A Thabet
- Rasha Abdeen Refaei
- Safaa Mohammed Elmahdy
Institutions
- Qassim University (SA)
- Sohag University (EG)
Publication Details
- Journal
- Heliyon
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e41043
- Citations
- 3
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.51
Funders
- Qassim University