Compulsion is associated with impaired goal-directed and habitual learning and responding in obsessive-compulsive disorder
The results indicate that patients with OCD exhibit deficits in updating the associative strength based on prediction errors and are more likely to doubt established correct associations during goal-directed and habitual learning. These deficits may contribute to the inflexible goal-directed behavioral control and are involved in the mechanism of compulsion in OCD.
Authors
- Xiongzhao Zhu (ORCID: https://orcid.org/0000-0002-7573-0740)
- Jie Xia (ORCID: https://orcid.org/0000-0003-4574-9376)
- Jingjie Lu
- Chuting Li
- Chuman Xiao (ORCID: https://orcid.org/0009-0001-9666-5001)
- Quanhao Yu
- Yanyuan Cao
- Jie Fan (ORCID: https://orcid.org/0000-0002-8461-6093)
- Feng Gao (ORCID: https://orcid.org/0000-0002-0319-2250)
- Xiang Wang (ORCID: https://orcid.org/0000-0001-5433-9905)
- Qian Liu (ORCID: https://orcid.org/0000-0001-5341-1290)
Institutions
- Central South University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Mental Health Center (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- International Journal of Clinical and Health Psychology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1016/j.ijchp.2024.100531
- Citations
- 2
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.28
Funders
- National Natural Science Foundation of China
- Hunan Provincial Innovation Foundation for Postgraduate