Altered brain regional homogeneity, depressive symptoms, and cognitive impairments in medication-free female patients with current depressive episodes in bipolar disorder and major depressive disorder
Cognitive impairment was more severe in female patients with BDE than in those with MDD. Changes in the ReHo values of the right putamen and left lobules IV-V may serve as unique neuroimaging markers for BDE. Alterations in the ReHo values of the left precuneus and left lobule VI could serve as common pathophysiological mechanisms for BDE and MDD in women and indicate depressive states.
Authors
- Shuzhan Gao (ORCID: https://orcid.org/0009-0000-4051-1276)
- Chaoyong Xiao
- Chenxi Ling
- Ting Peng (ORCID: https://orcid.org/0000-0003-1458-1603)
- Fan Wu (ORCID: https://orcid.org/0000-0003-1414-9896)
- Jing Sun (ORCID: https://orcid.org/0000-0002-4188-2260)
- Sulin Ni (ORCID: https://orcid.org/0000-0001-9056-9601)
- Xijia Xu (ORCID: https://orcid.org/0000-0002-0598-7188)
- Jing Jiang (ORCID: https://orcid.org/0009-0008-0489-2217)
Institutions
- Nanjing Brain Hospital (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1186/s12888-024-06352-4
- Citations
- 6
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- National Natural Science Foundation of China
- Nanjing Medical University