Efficacy and tolerability of single-fraction radiotherapy for spinal bone metastases in a low-middle-income country setting: a prospective study
The study confirms the efficacy and safety of single-fraction RT for spinal bone metastases, providing significant pain relief and lower skin toxicity relative to multiple fraction regimens. These results confirm the efficacy of single-fraction RT in the treatment of vertebral metastases also in resource-limited settings, suggesting its broader adoption to reduce toxicity and treatment burdens in low-middle-income countries.
Authors
- Md. Rahad Islam Bhuiyan (ORCID: https://orcid.org/0009-0000-5548-5250)
- Tasneem Hossain
- Erika Galietta (ORCID: https://orcid.org/0000-0001-5202-3472)
- A.G. Morganti (ORCID: https://orcid.org/0000-0001-9793-3410)
- Qazi Mushtaq Hussain (ORCID: https://orcid.org/0000-0001-8981-290X)
- Altaf Hossain (ORCID: https://orcid.org/0000-0002-3774-1588)
- Arina A. Zamfir
- AFM Kamal Uddin
- Nowshin Taslima Hossain
Institutions
- BRAC (BD)
- Khulna Medical College (BD)
- Azienda USL di Bologna (IT)
- National Institute of Cancer Research and Hospital (BD)
- University of Bologna (IT)
Publication Details
- Journal
- Supportive Care in Cancer
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1007/s00520-024-08972-8
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00