Unraveling the molecular dissociation between aging and atherosclerosis: A bioinformatics approach
Aging encompasses more than just the senescence of vascular cells; it is significantly affected by extracellular factors such as type I interferon. The onset of atherosclerosis, therefore, cannot be attributed solely to aging. Instead, it likely involves enhanced mechanisms such as phagocytosis and heighted lysosomal activity. Geriatr Gerontol Int 2025; 25: 108-115.
Authors
- Atsuya Shimizu (ORCID: https://orcid.org/0000-0001-5909-4716)
- Reo Kawano (ORCID: https://orcid.org/0000-0001-8699-3768)
- Manabu Kokubo
- Takahiro Kamihara (ORCID: https://orcid.org/0000-0003-4592-4170)
- Akihiro Hirashiki (ORCID: https://orcid.org/0000-0002-1123-1782)
- Tomoyasu Kinoshita
- Takuya Omura (ORCID: https://orcid.org/0000-0001-5490-8653)
- Ken Tanaka (ORCID: https://orcid.org/0000-0001-6664-5360)
- Seiya Tanaka
- Hidenori Arai (ORCID: https://orcid.org/0000-0002-9000-6849)
Institutions
- University of Hawaiʻi at Mānoa (US)
- National Center for Geriatrics and Gerontology (JP)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1111/ggi.15024
- Primary Topic
- Atherosclerosis and Cardiovascular Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Center for Geriatrics and Gerontology
- Japan Society for the Promotion of Science