Effect of atorvastatin on lipopolysaccharide-induced lung inflammation and hypoxia in mice; modulation of HIF-1α, CINC and MIP-2
Collectively, the present study suggests that, atorvastatin effectively protects against LPS-induced acute lung injury through inhibition of oxidative stress, inflammation, hypoxia, and neutrophil recruitment.
Authors
- Rania Elgohary (ORCID: https://orcid.org/0000-0002-2948-5449)
- Amany A. El‐Fadaly
- Abeer Salama (ORCID: https://orcid.org/0000-0001-9870-5583)
Institutions
- National Research Centre (EG)
- Energy Research Company (United States) (US)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1080/08923973.2024.2436089
- Citations
- 6
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 1.44