Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery

Malignant hyperthermia (MH) is a potentially fatal disorder triggered by volatile anesthetics or succinylcholine, inducing a hypermetabolic crisis in susceptible patients. The caffeine-halothane contracture test (CHCT) remains a gold standard for MH detection. The authors describe a pregnant patient with a history of exertional rhabdomyolysis, who required urgent MH screening for administration of MH-triggering anesthetics. This anesthetic plan allowed for an in utero myelomeningocele repair for a 24-week-old fetus. A multi-institutional team coordinated the urgent CHCT and repair with a favorable outcome.

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Journal
A&A Practice
Published
2024-12-01
DOI
https://doi.org/10.1213/xaa.0000000000001868
Citations
1
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.23
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article

Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery

Erin Tracy, Rachel E. Bridwell, David J. Berman, Luke Michaelson et al.
1 citations
A&A Practice
Ion channel regulation and function
0.23
article

Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery

Erin Tracy, Rachel E. Bridwell, David J. Berman, Luke Michaelson, Angela M. Curell, Maria D. Tischer
article en
1 citations

Abstract

Malignant hyperthermia (MH) is a potentially fatal disorder triggered by volatile anesthetics or succinylcholine, inducing a hypermetabolic crisis in susceptible patients. The caffeine-halothane contracture test (CHCT) remains a gold standard for MH detection. The authors describe a pregnant patient with a history of exertional rhabdomyolysis, who required urgent MH screening for administration of MH-triggering anesthetics. This anesthetic plan allowed for an in utero myelomeningocele repair for a 24-week-old fetus. A multi-institutional team coordinated the urgent CHCT and repair with a favorable outcome.

A&A PracticeVol. 18(12)
Johns Hopkins University (US), Uniformed Services University of the Health Sciences (US), Baltimore VA Medical Center (US)
Good health and well-being
Openalex Percentile: Top 40%
Ion channel regulation and function
0.23
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Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery — Erin Tracy, Rachel E. Bridwell, et al. · A&A Practice (2024) | TGRS Research Map | TGRS