Case Report of an Urgent Determination of Malignant Hyperthermia Status of a 24-Week Pregnant Patient Requiring Intrauterine Fetal Surgery
Malignant hyperthermia (MH) is a potentially fatal disorder triggered by volatile anesthetics or succinylcholine, inducing a hypermetabolic crisis in susceptible patients. The caffeine-halothane contracture test (CHCT) remains a gold standard for MH detection. The authors describe a pregnant patient with a history of exertional rhabdomyolysis, who required urgent MH screening for administration of MH-triggering anesthetics. This anesthetic plan allowed for an in utero myelomeningocele repair for a 24-week-old fetus. A multi-institutional team coordinated the urgent CHCT and repair with a favorable outcome.
Authors
- Erin Tracy (ORCID: https://orcid.org/0000-0001-6523-4156)
- Rachel E. Bridwell
- David J. Berman (ORCID: https://orcid.org/0000-0003-2750-4666)
- Luke Michaelson (ORCID: https://orcid.org/0000-0002-9651-3737)
- Angela M. Curell
- Maria D. Tischer
Institutions
- Johns Hopkins University (US)
- Uniformed Services University of the Health Sciences (US)
- Baltimore VA Medical Center (US)
Publication Details
- Journal
- A&A Practice
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1213/xaa.0000000000001868
- Citations
- 1
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 0.23