Molecular allergen sensitization drives phenotypes of severe asthma in children: Evidence from a megacity cohort (<scp>SAMP</scp>)
These results underline the heterogeneity of sensitization profiles in severe allergic childhood asthma. The most severe asthma phenotypes were associated with multiple sensitizations to both inhaled and food allergen molecular families as expected, and to the tropomyosin molecular family, a novel finding.
Authors
- Tamazoust Guiddir (ORCID: https://orcid.org/0000-0002-8452-9918)
- M. Bourgoin‐Heck (ORCID: https://orcid.org/0000-0001-6497-4830)
- Flore Amat
- Stéphanie Wanin (ORCID: https://orcid.org/0000-0001-6656-3461)
- Philippe Pierre
- Thierry Rose (ORCID: https://orcid.org/0000-0001-8863-0207)
- Fanny Rancière (ORCID: https://orcid.org/0000-0003-3485-2247)
- J. Just (ORCID: https://orcid.org/0000-0002-5646-2429)
- Yannick Chantran (ORCID: https://orcid.org/0000-0002-9778-0044)
- Isabelle Momas (ORCID: https://orcid.org/0000-0003-4344-3787)
- Sarah Saf (ORCID: https://orcid.org/0000-0002-2733-0590)
- Victoria Wolff‐Goldnadel
Institutions
- Hôpital américain de paris (FR)
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Institut Pasteur (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Sorbonne Paris Cité (FR)
- Centre de recherche en Epidémiologie et Santé des Populations (FR)
- Hôpital Robert-Debré (FR)
- Bicêtre Hospital (FR)
- Centre de Recherche Épidémiologie et Statistique (FR)
Publication Details
- Journal
- Pediatric Allergy and Immunology
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/pai.70014
- Citations
- 2
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- AstraZeneca
- Sanofi
- Regeneron Pharmaceuticals
- Aimmune Therapeutics
- Agence Nationale de la Recherche