Ataxia triggered by phenytoin: a clinical case report

Phenytoin is a commonly prescribed, cost-effective medication for epilepsy treatment, but it requires careful monitoring to prevent adverse effects in patients undergoing long-term therapy. Common side effects of phenytoin include abnormal muscle movements, slurred speech, ataxia, coordination difficulties, rashes, hepatotoxicity, aplastic anemia, and pancytopenia. In this case, a 30-year-old male patient, with a history of epilepsy, presented with symptoms of headache, blurred vision, and swaying while walking, with a tendency to veer to the right. He had been on regular phenytoin therapy (100 mg twice daily) for 10 years. After discontinuing phenytoin, his symptoms resolved, highlighting the need for regular monitoring of patients on long-term phenytoin therapy to detect and manage potential adverse effects.

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Publication Details

Journal
International Journal of Zoology Environment and Life Sciences
Published
2024-08-31
DOI
https://doi.org/10.70604/ijzels.v1i1.3
Primary Topic
Pharmacological Effects and Toxicity Studies
Type
article
Field-Weighted Citation Impact
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article

Ataxia triggered by phenytoin: a clinical case report

Md Baharul Islam, Renukaradhya Chitti, Venkata Nagaraju Gorre, Robin Gc et al.
International Journal of Zoology Environment and Life Sciences
Pharmacological Effects and Toxicity Studies
article

Ataxia triggered by phenytoin: a clinical case report

Md Baharul Islam, Renukaradhya Chitti, Venkata Nagaraju Gorre, Robin Gc, A Hafis, H R Anusha
article en

Abstract

Phenytoin is a commonly prescribed, cost-effective medication for epilepsy treatment, but it requires careful monitoring to prevent adverse effects in patients undergoing long-term therapy. Common side effects of phenytoin include abnormal muscle movements, slurred speech, ataxia, coordination difficulties, rashes, hepatotoxicity, aplastic anemia, and pancytopenia. In this case, a 30-year-old male patient, with a history of epilepsy, presented with symptoms of headache, blurred vision, and swaying while walking, with a tendency to veer to the right. He had been on regular phenytoin therapy (100 mg twice daily) for 10 years. After discontinuing phenytoin, his symptoms resolved, highlighting the need for regular monitoring of patients on long-term phenytoin therapy to detect and manage potential adverse effects.

International Journal of Zoology Environment and Life SciencesVol. 1(1)
Adana Numune Eğitim ve Araştırma Hastanesi (TR), Hindu College of Pharmacy (IN)
Good health and well-being
Openalex Percentile: Top 66%
Pharmacological Effects and Toxicity Studies
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