The management and clinical outcome of paracetamol poisoning in South African adults: A single-centre retrospective review
A high case fatality rate was observed in the studied population. Early identification of at-risk individuals and prompt initiation of NAC can reduce poor outcomes. Larger multicentre studies are needed to identify independent predictors of paracetamol-induced hepatoxicity and mortality in Africa.
Authors
- Carla Kotzé (ORCID: https://orcid.org/0000-0002-5015-9293)
- Elsie C. Kruger (ORCID: https://orcid.org/0000-0002-0312-5189)
- Jeremi Swanepoel (ORCID: https://orcid.org/0000-0002-9338-2911)
- Eric H. Decloedt (ORCID: https://orcid.org/0000-0003-1815-5150)
Institutions
- National Health Laboratory Service (ZA)
- Stellenbosch University (ZA)
- Tygerberg Hospital (ZA)
Publication Details
- Journal
- South African Medical Journal
- Published
- 2024-11-29
- DOI
- https://doi.org/10.7196/samj.2024.v114i12.1986
- Citations
- 1
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.47