Multicenter, Real‐World Clinical Evaluation of Alemtuzumab and Anti‐Thymocyte Globulin for Severe Acute T Cell‐Mediated Kidney Transplant Rejection

Mostly, severe TCMRs have good long-term graft survival and function after either alemtuzumab or rATG therapy. No significant differences between the two therapies were found in this real-world clinical experience. Alemtuzumab is an effective alternative to rATG for the treatment of severe TCMR.

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Publication Details

Journal
Clinical Transplantation
Published
2024-12-01
DOI
https://doi.org/10.1111/ctr.70046
Citations
3
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
1.52
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article

Multicenter, Real‐World Clinical Evaluation of Alemtuzumab and Anti‐Thymocyte Globulin for Severe Acute T Cell‐Mediated Kidney Transplant Rejection

Dennis A. Hesselink, Marieke van der Zwan, Erzsi Tegzess, Marlies E. J. Reinders et al.
3 citations
Clinical Transplantation
Renal Transplantation Outcomes and Treatments
1.52
article

Multicenter, Real‐World Clinical Evaluation of Alemtuzumab and Anti‐Thymocyte Globulin for Severe Acute T Cell‐Mediated Kidney Transplant Rejection

Dennis A. Hesselink, Marieke van der Zwan, Erzsi Tegzess, Marlies E. J. Reinders, Marian C. Clahsen‐van Groningen, Stefan P. Berger, Jan‐Stephan Sanders, Priya Vart, Brenda C. M. de Winter, Lukas K. van Vugt
article en
3 citations

Abstract

Mostly, severe TCMRs have good long-term graft survival and function after either alemtuzumab or rATG therapy. No significant differences between the two therapies were found in this real-world clinical experience. Alemtuzumab is an effective alternative to rATG for the treatment of severe TCMR.

Clinical TransplantationVol. 38(12)
University Medical Center Groningen (NL), University of Groningen (NL), Erasmus MC (NL), Albert Schweitzer Ziekenhuis (NL), Erasmus MC Cancer Institute (NL), Erasmus MC Transplant Institute, RWTH Aachen University (DE)
Good health and well-being
Openalex Percentile: Top 17%
Renal Transplantation Outcomes and Treatments
1.52
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