Prevalence of FLT3 gene mutation and its expression in Brazilian pediatric B-ALL patients: clinical implications
Our findings do not support the inclusion of <i>FLT3</i> as a routine marker in the risk stratification of B-ALL patients; nevertheless, FLT3 alterations may be relevant for guiding personalized treatment approaches in specific clinical contexts.
Authors
- José Carlos Córdoba (ORCID: https://orcid.org/0000-0002-7573-1647)
- Isis Maria Quezado Magalhães
- Felipe Magalhães Furtado (ORCID: https://orcid.org/0000-0001-8858-6656)
- Ricardo Camargo (ORCID: https://orcid.org/0000-0003-0592-8396)
- Agenor de Castro Moreira dos Santos Júnior (ORCID: https://orcid.org/0000-0001-8485-2603)
- Bruna C. Guido (ORCID: https://orcid.org/0000-0001-6397-1259)
- Estefânia Rodrigues Biojone (ORCID: https://orcid.org/0000-0001-6725-8215)
- Diêgo M. de Oliveira (ORCID: https://orcid.org/0000-0002-6044-1954)
- Robéria Mendonça de Pontes (ORCID: https://orcid.org/0000-0003-3608-8254)
- Larissa Lemos Mendanha Cavalcante
Institutions
- Universidade de Brasília (BR)
- Sabin Medicina Diagnostica (Brazil) (BR)
- Hospital Universitário de Brasília (BR)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2024-12-06
- DOI
- https://doi.org/10.3389/fped.2024.1505060
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Fundação de Apoio à Pesquisa do Distrito Federal