Metabolism and spatial transcription resolved heterogeneity of glutamine metabolism in cervical carcinoma
This finding suggests that the variation in glutamine metabolism is not uniform throughout the tumor. The differential expression of ASCT2 in different regions of cervical cancer tissues seems to play a key role in causing this heterogeneity. This research has opened up new avenues for exploring the glutamine metabolic characteristics of CSCC which is essential for developing more effective targeted therapies.
Authors
- Jianqing Zhu (ORCID: https://orcid.org/0000-0001-5736-7397)
- Ayshamgul Hasim
- Guzalinuer Abulizi
- Qian Liu (ORCID: https://orcid.org/0000-0001-5341-1290)
Institutions
- Xinjiang Medical University (CN)
- Fifth Affiliated Hospital of Xinjiang Medical University (CN)
- Tumor Hospital of Xinjiang Medical University (CN)
- Xinjiang University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1186/s12885-024-13275-6
- Citations
- 2
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Natural Science Foundation of Xinjiang