Correlation between changes in apathy and cognition in Alzheimer’s disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2)
Changes in apathy are mostly independent of cognitive changes and apathy response to MPH may be independent from cognition. These results are consistent with the view that apathy as a syndrome is related to but distinct from cognition.
Authors
- Krushnaa Sankhe (ORCID: https://orcid.org/0000-0003-0535-4935)
- Shankar Tumati (ORCID: https://orcid.org/0000-0001-5703-2044)
- Luc Rivet
- Suzanne Craft (ORCID: https://orcid.org/0000-0003-0591-8657)
- Allan I. Levey (ORCID: https://orcid.org/0000-0002-3153-502X)
- Anton P. Porsteinsson (ORCID: https://orcid.org/0000-0002-0166-1738)
- Danielle Soares Rocha Vieira (ORCID: https://orcid.org/0000-0001-6222-6142)
- Krista L. Lanctôt (ORCID: https://orcid.org/0000-0001-7024-6637)
- Alan J. Lerner (ORCID: https://orcid.org/0000-0001-9447-6154)
- Paul B. Rosenberg (ORCID: https://orcid.org/0000-0003-1106-4299)
- David Shade
- Jamie Perin (ORCID: https://orcid.org/0000-0002-5482-6620)
- Nathan Herrmann (ORCID: https://orcid.org/0000-0001-9277-6110)
- Prasad R. Padala (ORCID: https://orcid.org/0000-0003-1921-9806)
- Christopher H. van Dyck (ORCID: https://orcid.org/0000-0003-1779-097X)
- Olga Brawman‐Mintzer
- Jacobo Mintzer
Institutions
- Sunnybrook Health Science Centre (CA)
- Johns Hopkins University (US)
- Medical University of South Carolina (US)
- University of Toronto (CA)
- University Hospitals of Cleveland (US)
- Johns Hopkins Medicine (US)
- Yale University (US)
- Central Arkansas Veterans Healthcare System (US)
- Ralph H. Johnson VA Medical Center (US)
- University School (US)
- Wake Forest University (US)
- University of Rochester (US)
- Case Western Reserve University (US)
- University of Arkansas for Medical Sciences (US)
Publication Details
- Journal
- International Psychogeriatrics
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1016/j.inpsyc.2024.100012
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- U.S. Department of Defense
- Eli Lilly and Company
- Biogen
- Sunovion
- ACADIA Pharmaceuticals
- Eisai
- H. Lundbeck A/S
- National Institutes of Health
- Genentech
- National Institute on Aging
- National Institute of Mental Health