The Relationship Between Anticipated Gender Dysphoria and Intention to Use Longer-Acting Formulations of Pre-Exposure Prophylaxis for HIV in Transgender and Gender Expansive Texans

Longer-acting pre-exposure prophylaxis (LA PrEP) may trigger gender dysphoria in transgender and gender expansive (TGE) individuals and influence intentions to use it. This community-based participatory research project examined this relationship regarding three LA PrEP formulations. Overall, 513 TGE Texans responded to an online survey, and 410 were included in this analysis. Anticipated dysphoria was associated with lower intentions to use an annual implantable (β = −0.27, p < 0.001). Intentions to use a monthly oral and a bimonthly injectable were associated with gender identity. Including TGE individuals in the development of LA PrEP will improve uptake by identifying unique barriers.

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Publication Details

Journal
Transgender Health
Published
2024-12-04
DOI
https://doi.org/10.1089/trgh.2023.0230
Primary Topic
LGBTQ Health, Identity, and Policy
Type
article
Field-Weighted Citation Impact
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article

The Relationship Between Anticipated Gender Dysphoria and Intention to Use Longer-Acting Formulations of Pre-Exposure Prophylaxis for HIV in Transgender and Gender Expansive Texans

Phillip W. Schnarrs, Emmett Schelling, Aliza Norwood, John Oeffinger et al.
Transgender Health
LGBTQ Health, Identity, and Policy
article

The Relationship Between Anticipated Gender Dysphoria and Intention to Use Longer-Acting Formulations of Pre-Exposure Prophylaxis for HIV in Transgender and Gender Expansive Texans

Phillip W. Schnarrs, Emmett Schelling, Aliza Norwood, John Oeffinger, Julie A. Zuñiga, Elizabeth Mayfield Arnold, Gabrielle Benitez, Paul Fliedner, Gin Pham, TreShaun Pate, Madeleine Croll, Jacey Buchorn, Rocky Lane, Liany D. Serrano Oviedo, K. B. Brookins
article en

Abstract

Longer-acting pre-exposure prophylaxis (LA PrEP) may trigger gender dysphoria in transgender and gender expansive (TGE) individuals and influence intentions to use it. This community-based participatory research project examined this relationship regarding three LA PrEP formulations. Overall, 513 TGE Texans responded to an online survey, and 410 were included in this analysis. Anticipated dysphoria was associated with lower intentions to use an annual implantable (β = −0.27, p < 0.001). Intentions to use a monthly oral and a bimonthly injectable were associated with gender identity. Including TGE individuals in the development of LA PrEP will improve uptake by identifying unique barriers.

Transgender Health
Austin College (US), Texas Department of State Health Services (US), University of Kentucky (US), The University of Texas Rio Grande Valley (US), Action Network (US), Columbia University (US), The University of Texas at Austin (US), The University of Texas Health Science Center at Houston (US)
Gender equality
Openalex Percentile: Top 71%
LGBTQ Health, Identity, and Policy
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