Immediate postinjury extracorporeal carbon dioxide removal reduces ventilator requirements and mitigates acute respiratory distress syndrome in swine
In swine with severe smoke inhalation and burns, immediate postinjury ECCO 2 R reduced ventilator settings, delayed or prevented ARDS, and reduced its severity. Proactive early percutaneous ECCO 2 R initiation via simplified, purpose-built devices should be considered as a low-maintenance lung injury management approach with significant disease modifying clinical benefit potential.
Authors
- Leopoldo C. Cancio (ORCID: https://orcid.org/0000-0002-0066-1998)
- Bryan S. Jordan (ORCID: https://orcid.org/0000-0003-1928-4632)
- Daniel Wendorff (ORCID: https://orcid.org/0000-0002-7456-8964)
- Jeremy W. Cannon (ORCID: https://orcid.org/0000-0002-2969-9316)
- Teryn R. Roberts (ORCID: https://orcid.org/0000-0002-2460-6432)
- Brendan M. Beely (ORCID: https://orcid.org/0000-0001-9442-9462)
- Andriy I. Batchinsky (ORCID: https://orcid.org/0000-0001-8601-2827)
- Corina Necsoiu
- Kevin K. Chung (ORCID: https://orcid.org/0000-0002-2781-3787)
Institutions
- United States Army Institute of Surgical Research (US)
Publication Details
- Journal
- The Journal of Trauma: Injury, Infection, and Critical Care
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1097/ta.0000000000004486
- Citations
- 3
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.26