Clinical Implementation of Nephrologist-Led Genomic Testing for Glomerular Diseases in Singapore: Rationale and Protocol
This study will create and evaluate a nephrologist-led genetic service, develop an efficient variant curation process, and inform future recommendations on the optimal referral and genetic testing strategy for monogenic glomerular disease in Singapore. This will facilitate the future mainstreaming of genetic testing that will enable precision medicine in kidney care.
Authors
- Yaochun Zhang (ORCID: https://orcid.org/0000-0003-3220-3788)
- Irene Mok (ORCID: https://orcid.org/0000-0001-6796-6414)
- Jason Chon Jun Choo (ORCID: https://orcid.org/0000-0002-8477-0875)
- Hui Zhuan Tan (ORCID: https://orcid.org/0000-0003-4899-6399)
- Gek Cher Chan (ORCID: https://orcid.org/0000-0002-4661-3350)
- Ru Sin Lim
- Jiin Ying Lim (ORCID: https://orcid.org/0000-0003-3253-2768)
- Kar Hui Ng (ORCID: https://orcid.org/0000-0002-6919-8575)
- Regina Shaoying Lim
- Breana Cham (ORCID: https://orcid.org/0000-0002-2915-9846)
- Yong Hong Ng (ORCID: https://orcid.org/0000-0001-8884-1805)
- Tung Lin Lee (ORCID: https://orcid.org/0000-0001-9684-5830)
- Yi Da (ORCID: https://orcid.org/0000-0001-6970-7969)
- Jun Li Ng
- Cynthia Ciwei Lim (ORCID: https://orcid.org/0000-0003-0021-4861)
- Hui‐Lin Chin (ORCID: https://orcid.org/0000-0001-7431-6794)
- Sylvia Kam (ORCID: https://orcid.org/0000-0001-7704-1917)
- Esther Huimin Leow (ORCID: https://orcid.org/0000-0002-3504-7656)
- Indra Ganesan (ORCID: https://orcid.org/0000-0003-3065-4948)
- Jeannette Goh
- Mya Than
- See Cheng Yeo (ORCID: https://orcid.org/0000-0003-0857-4781)
- Jia Liang Kwek (ORCID: https://orcid.org/0000-0001-8161-1679)
- Celeste Yap
- Z.J. Wang (ORCID: https://orcid.org/0009-0005-1512-9397)
- Siew Le Chong
- Boon Wee Teo (ORCID: https://orcid.org/0000-0002-4911-8507)
- Naline Gandhi (ORCID: https://orcid.org/0000-0002-8456-174X)
- David Bruce Matchar (ORCID: https://orcid.org/0000-0003-3020-2108)
- Su Mein Goh
- Ee Shien Tan
- Sing Ming Chao
Institutions
- SingHealth (SG)
- National University of Singapore (SG)
- Duke University (US)
- Tan Tock Seng Hospital (SG)
- SingHealth Duke-NUS Academic Medical Centre (SG)
- KK Women's and Children's Hospital (SG)
- Duke-NUS Medical School (SG)
- National University Hospital (SG)
Publication Details
- Journal
- American Journal of Nephrology
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1159/000542942
- Citations
- 5
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- National Research Foundation
- National Research Foundation Singapore
- National Healthcare Group
- Medical Research Council
- National Medical Research Council
- National Cancer Institute