Renshen (Radix Ginseng) polysaccharide promotes repair of the mice intestinal mucosa through regulatory mechanisms based on polyamine and human antigen R.

Renshen (<i>Radix Ginseng</i>) polysaccharide-induced repair of intestinal mucosal injury may be mediated by increased cell migration <i>via</i> polyamine-based regulatory mechanisms. <i>In vitro</i> and <i>in vivo</i> experiments suggest that Renshen (<i>Radix Ginseng</i>) polysaccharide-induced post-transcriptional regulation of STIM1 and Cdc42 may be related to differences in the regulation of different target genes by HuR. Taken together, these data provide a reference for further exploration of the protective effect of Renshen (<i>Radix Ginseng</i>) on the intestinal mucosa.