[Diazepam alleviates pulmonary fibrosis in mice by inhibiting LPS-induced pyroptosis and inflammation <i>via</i> the let-7a-5p/MYD88 axis].
Diazepam can negatively regulate MYD88 by upregulating the expression of let-7a-5p to inhibit LPS-induced pyroptosis and inflammatory response, thereby alleviating lung fibrosis in mice.
Authors
- Kaixiong Tao (ORCID: https://orcid.org/0000-0002-7723-6121)
- Dong‐Keun Song (ORCID: https://orcid.org/0000-0002-9238-3816)
- Hua Li (ORCID: https://orcid.org/0000-0003-1903-836X)
- Yanping Li (ORCID: https://orcid.org/0000-0002-0412-2748)
- Xiaoyan Tang (ORCID: https://orcid.org/0000-0002-5536-5117)
Institutions
- Second People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-11-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.11.05
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article