Circulating and hepatic levels of growth differentiation factor 15 in patients with metabolic dysfunction‐associated steatotic liver disease
Increased hepatic and circulating GDF15 are found in MASLD. Treatment with GLP-1-RA may reduce GDF15, possibly reflecting beneficial metabolic and inflammatory effects.
Authors
- Gianluca Mazzoni (ORCID: https://orcid.org/0000-0003-2397-1064)
- Henning Hvid (ORCID: https://orcid.org/0000-0002-3667-4141)
- Mikkel Parsberg Werge (ORCID: https://orcid.org/0000-0002-9980-1072)
- Anders Ellekaer Junker (ORCID: https://orcid.org/0000-0002-4804-8308)
- Elisabeth D. Galsgaard (ORCID: https://orcid.org/0000-0002-0584-3803)
- Sebastian B. Jørgensen (ORCID: https://orcid.org/0000-0002-9648-0971)
- Cesar A. Prada‐Medina (ORCID: https://orcid.org/0000-0003-1939-2297)
- Josephine Grandt (ORCID: https://orcid.org/0000-0002-2308-2235)
- Nicolai J. Wewer Albrechtsen (ORCID: https://orcid.org/0000-0003-4230-5753)
- Mogens Vyberg (ORCID: https://orcid.org/0000-0002-6392-9517)
- Birgitte Martine Viuff (ORCID: https://orcid.org/0000-0002-1676-2531)
- Jonas Kildegaard (ORCID: https://orcid.org/0000-0003-0946-5587)
- Flemming Bendtsen (ORCID: https://orcid.org/0000-0002-8419-2104)
- Liv Eline Hetland (ORCID: https://orcid.org/0000-0001-8753-4096)
- Reza Rafiolsadat Serizawa (ORCID: https://orcid.org/0000-0002-3054-8689)
- Michael Richter (ORCID: https://orcid.org/0000-0002-0670-3634)
- Søren Møller (ORCID: https://orcid.org/0000-0001-9684-7764)
- Lea Mørch Harder (ORCID: https://orcid.org/0009-0007-6126-3380)
- Kristian Moss Bendtsen (ORCID: https://orcid.org/0009-0005-5914-2972)
- Elias Badal Rashu (ORCID: https://orcid.org/0000-0002-9958-9024)
- Anne‐Sofie Houlberg Jensen (ORCID: https://orcid.org/0000-0002-5982-8684)
- Mira Thing (ORCID: https://orcid.org/0009-0009-8924-9534)
- Lise Lotte Gluud (ORCID: https://orcid.org/0000-0002-9462-4468)
Institutions
- University of Copenhagen (DK)
- Novo Nordisk (Denmark) (DK)
- Frederiksberg Hospital (DK)
- Hvidovre Hospital (DK)
- Copenhagen University Hospital (DK)
- Novo Nordisk (United States) (US)
- Novo Nordisk (United Kingdom) (GB)
- Aalborg University (DK)
Publication Details
- Journal
- Hepatology Research
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1111/hepr.14148
- Citations
- 8
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- Novo Nordisk