Advanced MicroRNA delivery for lung inflammatory therapy: surfactant protein A controls cellular internalisation and degradation of extracellular vesicles
These findings underscore the potential of SP-A-EVs as highly effective drug delivery systems for targeted therapeutics in lung-related disorders, capitalising on the strong affinity between AMs and SP-A and the modulation of cellular internalisation.
Authors
- Heedoo Lee (ORCID: https://orcid.org/0000-0001-7652-3930)
- Miji Kim (ORCID: https://orcid.org/0000-0002-0852-8825)
- Sujeong Park (ORCID: https://orcid.org/0000-0001-6163-8962)
- Seon‐Jin Lee (ORCID: https://orcid.org/0000-0001-7214-7536)
- Jung Joo Hong (ORCID: https://orcid.org/0000-0002-9795-6513)
- Dohyun Kim (ORCID: https://orcid.org/0000-0002-0772-6985)
- Dong-Woo Kim (ORCID: https://orcid.org/0000-0002-2514-724X)
- Nayoung Lee (ORCID: https://orcid.org/0000-0002-6274-5740)
- Yang Jin (ORCID: https://orcid.org/0000-0002-4779-531X)
Institutions
- Boston University (US)
- Changwon National University (KR)
- Korean Register (South Korea) (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Thorax
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1136/thorax-2024-221793
- Citations
- 4
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Research Foundation
- Korea Institute of Science and Technology
- Korea Research Institute of Bioscience and Biotechnology
- Korea Basic Science Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea