Blood-brain barrier disruption mediates the association between cerebral small vessel disease and clinical outcome after stroke: a secondary analysis of the Lesion Evolution in Stroke and Ischemia on Neuroimaging study
These findings suggest a possible association between severe diffuse HARM and WMH severity. The relationship between WMH severity and early stroke outcome may be mediated by blood-brain barrier disruption.
Authors
- Lawrence L. Latour (ORCID: https://orcid.org/0000-0001-6160-5263)
- Marie L. Luby (ORCID: https://orcid.org/0000-0001-7698-5123)
- Rebecca F. Gottesman (ORCID: https://orcid.org/0000-0002-9504-1256)
- Kyle C. Kern (ORCID: https://orcid.org/0000-0002-2703-7669)
- Derrick Okine (ORCID: https://orcid.org/0000-0001-7433-030X)
Institutions
- West Los Angeles College (US)
- National Institutes of Health (US)
- University of California, Los Angeles (US)
- National Institute of Neurological Disorders and Stroke (US)
Publication Details
- Journal
- Frontiers in Stroke
- Published
- 2024-12-04
- DOI
- https://doi.org/10.3389/fstro.2024.1510359
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health