Proinflammatory Cytokine Profiles in Menière's Disease and Vestibular Migraine

This pilot study suggests Menière's disease patients may have higher levels of TNF-α and IFN-γ and lower levels of ENA-78 than vestibular migraine patients when measured following in vitro release from patient-derived PBMC. Increased sample size, optimized blood draw timing, and more specific PBMC stimulation may help us further elucidate inflammatory pathways implicated in these disorders.

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Publication Details

Journal
Otology & Neurotology
Published
2024-11-20
DOI
https://doi.org/10.1097/mao.0000000000004372
Citations
6
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
1.48
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article

Proinflammatory Cytokine Profiles in Menière's Disease and Vestibular Migraine

John E. Baatz, Carol L. Wagner, Danforth A. Newton, Sunny Shah et al.
6 citations
Otology & Neurotology
Vestibular and auditory disorders
1.48
article

Proinflammatory Cytokine Profiles in Menière's Disease and Vestibular Migraine

John E. Baatz, Carol L. Wagner, Danforth A. Newton, Sunny Shah, Habib G. Rizk, Shaun A. Nguyen, Neil P. Monaghan, Brian Keith
article en
6 citations

Abstract

This pilot study suggests Menière's disease patients may have higher levels of TNF-α and IFN-γ and lower levels of ENA-78 than vestibular migraine patients when measured following in vitro release from patient-derived PBMC. Increased sample size, optimized blood draw timing, and more specific PBMC stimulation may help us further elucidate inflammatory pathways implicated in these disorders.

Otology & NeurotologyVol. 46(1)
Albert Einstein College of Medicine (US), Campbell University (US), Medical University of South Carolina (US)
Good health and well-being
Openalex Percentile: Top 17%
Vestibular and auditory disorders
1.48
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Proinflammatory Cytokine Profiles in Menière's Disease and Vestibular Migraine — John E. Baatz, Carol L. Wagner, et al. · Otology & Neurotology (2024) | TGRS Research Map | TGRS