Seroprevalence study reveals pertussis underreporting in Brazil and calls for adolescent/young adult boosting: mouse model demonstrates immunity restoration
Pertussis appears to circulate predominantly among adolescents and young adults. Insights from the mouse model indicate that immunity can be restored with booster doses. Boosting immunity in non-targeted groups could prevent the dissemination of pertussis to infants.
Authors
- Eliane Pereira da Silva (ORCID: https://orcid.org/0000-0002-3364-5046)
- Monalisa Martins Trentini (ORCID: https://orcid.org/0000-0002-3207-8967)
- Filumena Maria da Silva Gomes (ORCID: https://orcid.org/0000-0002-0889-231X)
- Renan P. Souza (ORCID: https://orcid.org/0000-0002-9479-4432)
- Ricardo Palácios (ORCID: https://orcid.org/0000-0002-1410-8579)
- Dúnia Rodriguez (ORCID: https://orcid.org/0000-0001-9779-1280)
- Maria Helena Valente
- Priscila S. Cunegundes
- Carlos Eduardo Madureira Trufen (ORCID: https://orcid.org/0000-0003-1216-0418)
- Isaı́as Raw
- Alex I. Kanno (ORCID: https://orcid.org/0000-0002-4731-1493)
- Luciana C. C. Leite (ORCID: https://orcid.org/0000-0003-0156-1312)
- Arthur D. Januzzi
- Lais S. Yamamoto
- Waldely O. Dias
Institutions
- Universidade Federal de Minas Gerais (BR)
- Instituto Butantan (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.3389/fimmu.2024.1472157
- Citations
- 5
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Universidade de São Paulo
- Banco Nacional de Desenvolvimento Econômico e Social