Alternative splicing regulation by tumor suppressing subtransferable candidate 4: a pathway to tumor suppression
These findings demonstrate that TSSC4 plays a crucial role in regulating RNA splicing, particularly in controlling the splicing of many oncogenes. Our results reveal a novel mechanism by which TSSC4 mediates tumor suppression through the modulation of alternative splicing, which could provide implications for understanding TSSC4's role in cancer biology.
Authors
- Duanwu Zhang (ORCID: https://orcid.org/0000-0003-2946-846X)
- Gaigai Wei (ORCID: https://orcid.org/0000-0002-9026-7301)
- Jingjing Yi (ORCID: https://orcid.org/0000-0001-9119-2324)
- Nana Wu (ORCID: https://orcid.org/0000-0002-1458-679X)
- Haiping Zhao (ORCID: https://orcid.org/0000-0002-3982-3624)
- Yuqi Zhang (ORCID: https://orcid.org/0000-0001-9577-3150)
- Huiling Zhang (ORCID: https://orcid.org/0000-0001-8348-7616)
- Tingting Ren (ORCID: https://orcid.org/0000-0002-6226-6504)
- Zhihan Guo (ORCID: https://orcid.org/0009-0004-7638-6779)
- Yihan Wang (ORCID: https://orcid.org/0000-0002-0541-0960)
- Zixi Wang (ORCID: https://orcid.org/0000-0002-3914-148X)
Institutions
- Children's Hospital of Fudan University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.3389/fimmu.2024.1474527
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.23