Comparative Anti-Anaemia Efficacy of Jatropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced -Anaemia in Albino Rats

Anaemia is a blood illness that threatens public health. The anti-anaemia property of Jatropha tanjorensis and Telfairia occidentalis is known. However, information on their respective measures of anti-anaemia potential is veiled. Comparing the anti-anaemia potential of extracts from the said plants is pivoted in this investigation. J. tanjorensis (JTLE) and T. occidentalis (TOLE) leaves were ground into a fine powder and then macerated. Twenty-one (21) mature male albino rats were divided into seven groups of three (3) rats per group. Anaemia was induced in groups IIVII, after which extracts were administered orally for 21 consecutive days. Group I (normal control) and Group II were not administered extract. The third and fourth groups received 200 mg/kg of T. occidentalis and J. tanjorensis leaf extract, respectively. Groups V and VI received 400 mg/kg of T. occidentalis and J. tanjorensis leaf extracts, respectively. Group VII received extract composite (1:1). Standard techniques were used to evaluate the major anaemia indices. Findings regarding the relative anti-anaemia effectiveness of J. tanjorensis and T. occidentalis leaf extracts revealed that the extracts did not prevent the treated animals' body weight from increasing. Additionally, 200 mg/kg of the composite extract was found to significantly (p< 0.05) raise blood parameters above those reported for their respective components. PCV value recorded with 400 mg/kg bw of TOLE was considerably (p < 0.05) greater than that reported for JTLE. In conclusion, T. occidentalis had a better anti-anaemia potential.

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Publication Details

Journal
Tropical Journal of Phytochemistry and Pharmaceutical Sciences
Published
2024-12-03
DOI
https://doi.org/10.26538/tjpps/v3i8.4
Primary Topic
Ginger and Zingiberaceae research
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article
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article

Comparative Anti-Anaemia Efficacy of Jatropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced -Anaemia in Albino Rats

Tropical Journal of Phytochemistry and Pharmaceutical Sciences
Ginger and Zingiberaceae research
article

Comparative Anti-Anaemia Efficacy of Jatropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced -Anaemia in Albino Rats

article en

Abstract

Anaemia is a blood illness that threatens public health. The anti-anaemia property of Jatropha tanjorensis and Telfairia occidentalis is known. However, information on their respective measures of anti-anaemia potential is veiled. Comparing the anti-anaemia potential of extracts from the said plants is pivoted in this investigation. J. tanjorensis (JTLE) and T. occidentalis (TOLE) leaves were ground into a fine powder and then macerated. Twenty-one (21) mature male albino rats were divided into seven groups of three (3) rats per group. Anaemia was induced in groups IIVII, after which extracts were administered orally for 21 consecutive days. Group I (normal control) and Group II were not administered extract. The third and fourth groups received 200 mg/kg of T. occidentalis and J. tanjorensis leaf extract, respectively. Groups V and VI received 400 mg/kg of T. occidentalis and J. tanjorensis leaf extracts, respectively. Group VII received extract composite (1:1). Standard techniques were used to evaluate the major anaemia indices. Findings regarding the relative anti-anaemia effectiveness of J. tanjorensis and T. occidentalis leaf extracts revealed that the extracts did not prevent the treated animals' body weight from increasing. Additionally, 200 mg/kg of the composite extract was found to significantly (p< 0.05) raise blood parameters above those reported for their respective components. PCV value recorded with 400 mg/kg bw of TOLE was considerably (p < 0.05) greater than that reported for JTLE. In conclusion, T. occidentalis had a better anti-anaemia potential.

Tropical Journal of Phytochemistry and Pharmaceutical SciencesVol. 3(8)
Ahmadu Bello University (NG), University of Health Science (KH), University of Health Sciences (SO), University of Maiduguri (NG), Federal University of Technology Minna (NG)
Good health and well-being
Openalex Percentile: Top 71%
Ginger and Zingiberaceae research
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Comparative Anti-Anaemia Efficacy of Jatropha tanjorensis and Telfairia occidentalis Leaf Extracts in Aluminium Chloride (AlCl₃) Induced -Anaemia in Albino Rats · Tropical Journal of Phytochemistry and Pharmaceutical Sciences (2024) | TGRS Research Map | TGRS