Trends and factors associated with depression among adults in the United States

<b>Purpose</b>: Examine the trends and risk factors of depression among adults in the USA.<br /> <b>Methods: </b>The national health interview survey (NHIS) data were analyzed. NHIS early release data provided the prevalence of depression from 2019 to 2022. We assessed depression covariates using SPSS 29.<br /> <b>Results: </b>The prevalence of depression decreased from 4.7% in 2019 to 4.5% in 2020, before rising to 5% in 2022. Of 31,536 participants in 2022 NHIS, 51.7% were female and 40% were 26 to 49 years old. Logistic regression showed that being female, obese and having diabetes and lower level of education as well as smoking cigarettes were significantly associated with higher levels of depression. Conversely, being married and aged 60 years<sup>+</sup> were significantly associated with lower likelihood of depression.<br /> <b>Conclusion: </b>The decrease trends of depression at the onset the pandemic underscores the needs for further study. Targeted public health strategies and collaborative efforts are essential to mitigate depression’s impact and improve mental health outcomes.