Endothelial Angpt2 Promotes Adipocyte Progenitor Cells Maturation to Increase Visceral Adipose Tissue Accumulation
ECs are essential for promoting VAT accumulation by facilitating APC differentiation from MSLN to CFD phenotype. This process is driven by Angpt2 from ECs upon JAK1/STAT3 signalling activation under metabolic stress.
Authors
- Xianhao Yi (ORCID: https://orcid.org/0000-0002-1079-986X)
- Yan Tang (ORCID: https://orcid.org/0000-0002-9114-6536)
- Jingjing Cai (ORCID: https://orcid.org/0009-0004-9470-067X)
- Liyong Zhu (ORCID: https://orcid.org/0000-0002-4666-8458)
- Jiapu Ling (ORCID: https://orcid.org/0000-0002-9369-4886)
- Shaihong Zhu
Institutions
- Central South University (CN)
- Wuhan University (CN)
- Third Xiangya Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Diabetes/Metabolism Research and Reviews
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1002/dmrr.70012
- Citations
- 3
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.16