Posterior iliac crest vs. proximal tibia: distinct sources of anti-inflammatory and regenerative cells with comparable 6-month clinical outcomes in treatment of osteoarthritis
The results indicate that the iliac crest yields a higher concentration of MSCs compared to the proximal tibia, however both BM, independently of the MSCs concentration, show a beneficial clinical outcome in the treatment of knee OA. Furthermore, BMA is not superior to PRP treatment.
Authors
- Franco Lucio Gorgoglione
- Luis Emilio Savastano (ORCID: https://orcid.org/0000-0002-9881-1594)
- Marco Sandri (ORCID: https://orcid.org/0000-0002-1422-5695)
- Vitor Guerra (ORCID: https://orcid.org/0000-0003-3144-8062)
- Eugenio Caradonna (ORCID: https://orcid.org/0000-0001-9729-6722)
- Antônio Rossi (ORCID: https://orcid.org/0000-0003-3295-0345)
- Paolo Graziano (ORCID: https://orcid.org/0000-0001-7066-7896)
- Elisabetta Mormone (ORCID: https://orcid.org/0000-0001-5901-3760)
- Carmela Cisternino
- Elisabetta De Santis
- Massimiliano Copetti (ORCID: https://orcid.org/0000-0002-7960-5947)
- G. Di Maggio
- Nicola Pio Sinisi
- Francesco Maruccia (ORCID: https://orcid.org/0000-0002-1496-1326)
- Gíanni Biancofiore (ORCID: https://orcid.org/0000-0002-3755-1434)
Institutions
- Casa Sollievo della Sofferenza (IT)
- Centro Diagnostico Italiano (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Brescia (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1186/s12967-024-05924-y
- Citations
- 4
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.88