An observational post-authorization study to assess the effectiveness of a single dose Ad26.COV2.S for the prevention of COVID-19 using real-world data
This population-representative cohort study in U.S. clinical practice showed that a single dose of Ad26.COV2.S is effective for at least 12 months against several COVID-19 related outcomes. Individuals who were vaccinated with a single dose of Ad26.COV2.S were at lower risk for developing COVID-19, for being hospitalized for COVID-19, and for all-cause mortality temporally associated with COVID-19 compared to unvaccinated individuals in the U.S. during Alpha, Delta, and Omicron BA.1, BA.2, BA.212.1, and BA.5 variants circulation.
Authors
- Michael Batech (ORCID: https://orcid.org/0000-0001-9570-8180)
- Ann M. Madsen (ORCID: https://orcid.org/0000-0002-9206-708X)
- Amelia K. Boehme (ORCID: https://orcid.org/0000-0001-7408-1075)
- Lexie Rubens
- Raymond A. Harvey
- Deborah Ricci
- Mawuli Nyaku (ORCID: https://orcid.org/0000-0002-8846-2298)
- Astra Toyip
Institutions
- Johnson & Johnson (United States) (US)
- Aetion (United States) (US)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2024-12-04
- DOI
- https://doi.org/10.3389/fpubh.2024.1501919
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39