Zhuanggu Shubi ointment mediated the characteristic bacteria-intestinal mucosal barrier-bone metabolism axis to intervene in postmenopausal osteoporosis
ZGSBG promoted bone formation, inhibited bone resorption, regulated gut microbiota, repaired intestinal mucosal barrier damage, and inhibited intestinal inflammatory responses in PMO rats. <i>Muribaculaceae</i> and <i>Prevotella</i> might play positive roles in ZGSBG treatment of intestinal mucosal barrier injury and inflammatory reactions in PMO.
Authors
- Jiali Yuan (ORCID: https://orcid.org/0000-0003-2236-0827)
- Yueying Wu (ORCID: https://orcid.org/0000-0002-2608-6338)
- Yu Ren (ORCID: https://orcid.org/0000-0003-3123-9949)
- Yuan Ma (ORCID: https://orcid.org/0000-0002-0207-3620)
- Ning Li (ORCID: https://orcid.org/0000-0003-0856-3062)
- Xiaoya Li (ORCID: https://orcid.org/0000-0001-9071-5656)
- Lei Li (ORCID: https://orcid.org/0000-0002-6702-2584)
- Lan Sun
- Pei Huan
Institutions
- Yunnan University (CN)
- Third People's Hospital of Yunnan Province (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.3389/fcimb.2024.1500111
- Citations
- 1
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.23