Gut eutrophication

"Classical eutrophication" occurs when raw unfixed nutrients enter an aquatic environment. This causes the deleterious proliferation in fauna most adept at exploiting this abundance of nutrition. The net effect is de-diversification. We propose an analogous process in the gut: "gut eutrophication". Evidence shows that consumption of processed food, high in unfixed disaccharides, causes an expansion of bacteria in the gut habitat with a metabolic proclivity for these nutrients. This is at the expense of microbiota with a predilection for complex macromolecule macronutrients. There is a loss of diversity and the effect is exacerbated by a sedentary lifestyle. Gut luminal low oxygen tension favors salubrious gut commensals. This effect is potentiated by exercise but thwarted by inactivity. Antibiotics cause an obvious gut dysbiosis. So too can diet in a more insidious manner. The transition in microbial composition, seen in "gut eutrophication", may be an aetiological component of metabolic disease-associated gut dysbiosis.

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Publication Details

Journal
Frontiers in Microbiomes
Published
2024-12-04
DOI
https://doi.org/10.3389/frmbi.2024.1481250
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
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article

Gut eutrophication

Chika Edward Uzoigwe
Frontiers in Microbiomes
Diet and metabolism studies
article

Gut eutrophication

Chika Edward Uzoigwe
article en

Abstract

No abstract available for this paper.

Frontiers in MicrobiomesVol. 3
Openalex Percentile: Top 69%
Diet and metabolism studies
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