Gr-1 blockade remodels the immunosuppressive microenvironment induced by incomplete microwave ablation of hepatocellular carcinoma
Our data suggests that iMWA and Gr-1 blocking combined therapy can further inhibit HCC growth and significantly improve the CD8<sup>+</sup> T cells in the mouse subcutaneous tumor model, which brings good news to HCC patients.
Authors
- Zhouxiao Li (ORCID: https://orcid.org/0000-0002-5121-9681)
- Shipeng Dai (ORCID: https://orcid.org/0000-0001-6321-7774)
- Hongying Cao (ORCID: https://orcid.org/0000-0001-6207-0168)
- Yonghua Zhu (ORCID: https://orcid.org/0000-0002-0252-9464)
- Shuxian Zhu
- Han-Yuan Liu (ORCID: https://orcid.org/0000-0003-0294-3216)
- Chuan Liu (ORCID: https://orcid.org/0000-0002-6362-0261)
- Han Zhuo (ORCID: https://orcid.org/0000-0002-2349-5750)
- Zhengqing Lu
- Jinhua Song (ORCID: https://orcid.org/0000-0002-4802-690X)
- Chengyu Lv (ORCID: https://orcid.org/0009-0009-0028-4166)
- Tian Huang
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- Zhongda Hospital Southeast University (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1186/s12935-024-03578-w
- Citations
- 6
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- National Natural Science Foundation of China
- Nanjing Medical University