Invasive Aspergillosis With Multiple Locations, Mediastinitis, and Cardiac Invasion

A 25-year-old man reporting weight loss and constitutional symptoms was empirically treated for tuberculosis. Following acute seizures, the patient underwent cerebral imaging and was diagnosed with multiple nonischemic cerebral lesions. Thoracic imaging revealed fibrosing mediastinitis infiltrating and obscuring the left atrium and left ventricle. Results of a skin nodule biopsy revealed fungal hyphae, and invasive aspergillosis was finally diagnosed.

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Publication Details

Journal
JACC Case Reports
Published
2024-12-01
DOI
https://doi.org/10.1016/j.jaccas.2024.102770
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
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Invasive Aspergillosis With Multiple Locations, Mediastinitis, and Cardiac Invasion

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Invasive Aspergillosis With Multiple Locations, Mediastinitis, and Cardiac Invasion

Yamasandi Siddegowda Shrimanth, Nishtha Ahuja, Manish Shaw, Aditya Kumar, Manphool Singhal, Anil K. Choudhary, Navjyot Kaur, Suraj Kumar, Manoj Kumar Rohit
article en

Abstract

A 25-year-old man reporting weight loss and constitutional symptoms was empirically treated for tuberculosis. Following acute seizures, the patient underwent cerebral imaging and was diagnosed with multiple nonischemic cerebral lesions. Thoracic imaging revealed fibrosing mediastinitis infiltrating and obscuring the left atrium and left ventricle. Results of a skin nodule biopsy revealed fungal hyphae, and invasive aspergillosis was finally diagnosed.

JACC Case ReportsVol. 29(23)
NIMS University (IN), Sri Jayadeva Institute of Cardiovascular Sciences and Research (IN), Post Graduate Institute of Medical Education and Research (IN)
Zero hunger
Openalex Percentile: Top 72%
Antifungal resistance and susceptibility
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