TTF-1 negativity in synchronous M1b/M1c wildtype lung adenocarcinoma brain metastases predicts worse survival with increased risk of intracranial progression

In synchronous LUAD brain metastases, TTF-1 negativity reflects an aggressive phenotype with larger proliferation capacity and tumor volume. Future research should explore the underlying cellular and molecular alterations of this phenotype.

Authors

Institutions

Publication Details

Journal
Journal of Neuro-Oncology
Published
2024-12-04
DOI
https://doi.org/10.1007/s11060-024-04885-y
Citations
4
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
1.68

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

TTF-1 negativity in synchronous M1b/M1c wildtype lung adenocarcinoma brain metastases predicts worse survival with increased risk of intracranial progression

Helena Radbruch, Peter Vajkoczy, Nadja Jung, Jan Bukatz et al.
4 citations
Journal of Neuro-Oncology
Lung Cancer Treatments and Mutations
1.68
article

TTF-1 negativity in synchronous M1b/M1c wildtype lung adenocarcinoma brain metastases predicts worse survival with increased risk of intracranial progression

Helena Radbruch, Peter Vajkoczy, Nadja Jung, Jan Bukatz, Atik Baborie, R. Ates, Katharina Faust, Philip Bischoff, Nikolaj Frost, David Capper, Nils Ole Schmidt, David Horst, Julia Onken, Markus J. Riemenschneider, Anton Früh, Martin Witzenrath, Frank L. Heppner, Martin Proescholdt, Majd Abdulhamid Samman, David Wasilewski, Tommaso Araceli, Selin Murad, Julia Jünger, Arend Koch
article en
4 citations

Abstract

In synchronous LUAD brain metastases, TTF-1 negativity reflects an aggressive phenotype with larger proliferation capacity and tumor volume. Future research should explore the underlying cellular and molecular alterations of this phenotype.

Journal of Neuro-OncologyVol. 171(3)
German Cancer Research Center (DE), Heidelberg University (DE), King Fahd Medical City (SA), University Hospital Regensburg (DE), Humboldt-Universität zu Berlin (DE), Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Charité – Universitätsmedizin Berlin, Deutschen Konsortium für Translationale Krebsforschung, Berlin Institute of Health
Good health and well-being
Openalex Percentile: Top 14%
Lung Cancer Treatments and Mutations
1.68
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.