Differences in uni-dimensional breathlessness measures and thresholds for clinical response in a randomised controlled trial in people with chronic breathlessness: an exploratory study
Consistent with other recent work, worst breathlessness may be an important uni-dimensional outcome in evaluating chronic breathlessness clinically and in research. This study does not support a differential between unpleasantness now and breathlessness now, previously observed in laboratory-generated, acute-on-chronic breathlessness. Timeframe for recall (now or the last 24 hours) and the threshold for a clinical meaningful improvement (absolute (8.9 mm) or relative (15%)) affect assessment performance.
Authors
- David C. Currow (ORCID: https://orcid.org/0000-0003-1988-1250)
- Philip McCloud (ORCID: https://orcid.org/0000-0001-5570-2905)
- Magnus Per Ekström (ORCID: https://orcid.org/0000-0002-7227-5113)
- Katherine Clark (ORCID: https://orcid.org/0000-0001-5438-9064)
- Sandra Louw
- Diana Ferreira (ORCID: https://orcid.org/0000-0002-2554-8457)
- Miriam J. Johnson (ORCID: https://orcid.org/0000-0001-6204-9158)
Institutions
- Lund University (SE)
- University of Hull (GB)
- University of Wollongong (AU)
- Northern Sydney Local Health District (AU)
- Hull York Medical School (GB)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-002370
- Citations
- 1
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Helsinn
- Australian Government
- Department of Health and Aged Care, Australian Government