Ascorbic acid supplementation in adolescent rats ameliorates anxiety‐like and depressive‐like manifestations of nicotine‐ethanol abstinence: Role of oxidative stress, inflammatory, and serotonergic mechanisms
The present findings support the beneficial effect of Vit C on anxiety- and depressive-like behavior induced by Nic-Eth withdrawal through various mechanisms such as the promotion of antioxidant defense, suppression of inflammatory mediators, and enhancement of serotoninergic function.
Authors
- M Mahdizadeh (ORCID: https://orcid.org/0000-0002-9116-3037)
- S. Mohammad Ahmadi‐Soleimani (ORCID: https://orcid.org/0000-0003-3288-945X)
- Farimah Beheshti (ORCID: https://orcid.org/0000-0003-1524-2339)
- Alireza Najafzadeh
- A R Ostad Rahimi
- Samaneh Kakhki
Institutions
- Torbat Heydarieh University of Medical Sciences (IR)
Publication Details
- Journal
- International Journal of Developmental Neuroscience
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1002/jdn.10392
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.16