A ratiometric two-photon fluorescent probe for the quantification of nitroreductase in hypoxic neurons
We developed a novel ratiometric two-photon fluorescent probe for the selective and precise detection of nitroreductase (NTR) in neurons. Using this probe, we found that hypoxic stimulation could up-regulate endogenous NTR levels.
Authors
- Qian‐Shou Zong
- Longhua Guo (ORCID: https://orcid.org/0000-0003-0706-0973)
- Jianguo Xu (ORCID: https://orcid.org/0000-0002-0187-2623)
- Bingyong Lin
- Hong Hsin Huang (ORCID: https://orcid.org/0000-0002-3375-7910)
- Zhiquan Tang (ORCID: https://orcid.org/0000-0002-7141-9461)
- Shumei Gao (ORCID: https://orcid.org/0000-0002-6176-5483)
- Yuanyuan Yao (ORCID: https://orcid.org/0000-0002-7513-2919)
- Wanpeng Hu
- Yangang Wang
Institutions
- Jiaxing University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1039/d4cc06218c
- Citations
- 5
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- National Natural Science Foundation of China