Levistolide a Attenuates Acute Kidney Injury in Mice by Inhibiting the TLR-4/NF-κB Pathway
Levistolide A mitigates acute kidney injury through its antioxidative properties and modulation of the TLR-4/NF-κB signaling pathway. These findings provide valuable insights into the therapeutic potential of LA for AKI treatment and lay the groundwork for further mechanistic studies.
Authors
- Minghuang Gao (ORCID: https://orcid.org/0000-0002-1334-8378)
- Yousheng Mo (ORCID: https://orcid.org/0000-0001-7599-6015)
- Jiaying Cai
- Jiahui Shi (ORCID: https://orcid.org/0009-0004-2739-8634)
- Shuangwei Li (ORCID: https://orcid.org/0000-0003-2880-5508)
- Lanjie Yi (ORCID: https://orcid.org/0009-0001-2938-3100)
- Qi Wang (ORCID: https://orcid.org/0000-0002-6643-8561)
- Cong Yang (ORCID: https://orcid.org/0009-0003-6652-0527)
- Yujie Ma (ORCID: https://orcid.org/0009-0002-8401-054X)
Institutions
- Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-12-01
- DOI
- https://doi.org/10.2147/dddt.s476548
- Citations
- 10
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 3.39
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province