Uncovering cellular senescence as a therapeutic target in NF2-related vestibular schwannoma

These findings suggest that a one-two punch strategy of pro-senescence therapy induced by chemotherapy treatment followed by senolytic therapy represents a new paradigm for the pharmacological treatment of VS.

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Publication Details

Journal
Hearing Research
Published
2024-12-04
DOI
https://doi.org/10.1016/j.heares.2024.109165
Citations
3
Primary Topic
Vestibular and auditory disorders
Type
article
Field-Weighted Citation Impact
0.74
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article

Uncovering cellular senescence as a therapeutic target in NF2-related vestibular schwannoma

Ana M Jiménez-Lara, Isabel Varela‐Nieto, Luis Lassaletta, Julio R. Contreras et al.
3 citations
Hearing Research
Vestibular and auditory disorders
0.74
article

Uncovering cellular senescence as a therapeutic target in NF2-related vestibular schwannoma

Ana M Jiménez-Lara, Isabel Varela‐Nieto, Luis Lassaletta, Julio R. Contreras, Sandra Franco-Caspueñas, Carmen García-Montoya
article en
3 citations

Abstract

These findings suggest that a one-two punch strategy of pro-senescence therapy induced by chemotherapy treatment followed by senolytic therapy represents a new paradigm for the pharmacological treatment of VS.

Hearing ResearchVol. 455
Instituto Cajal (ES), Hospital La Paz Institute for Health Research (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Universidad Autónoma de Madrid (ES)
Zero hunger
Openalex Percentile: Top 27%
Vestibular and auditory disorders
0.74
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