The fuzzy MAD stroke conjecture, using Fuzzy C Means to classify multimodal apparent diffusion for ischemic stroke lesion stratification
The data analyzed included a small number of clinical patients without follow-up or contemporaneous histology; therefor, the findings and theorizing should be treated as conjecture. Nevertheless, each identified NAT and lesion type is consistent with the known underpinnings of physiological tissues and pathological ischemic stroke lesion (stage) types. Several findings should be considered in current clinical imaging: WM fluid accumulation, BBB compromise conundrum, b<sub>1000</sub> identified core may not be dead tissue, and a practical reason for DWI (pseudo) normalization.
Authors
- Kejia Cai (ORCID: https://orcid.org/0000-0003-1511-4273)
- Rifeng Jiang (ORCID: https://orcid.org/0000-0001-6959-0027)
- Changliang Su (ORCID: https://orcid.org/0000-0002-4418-5823)
- Chuanmiao Xie (ORCID: https://orcid.org/0000-0001-8533-623X)
- Mehran Shaghaghi (ORCID: https://orcid.org/0000-0002-0278-9936)
- Tibor Vályi-Nagy (ORCID: https://orcid.org/0000-0003-1212-584X)
- Weiguo Li (ORCID: https://orcid.org/0000-0001-8125-3824)
- Thomas Anderson
- Jay S. Tsuruda
- Frederick C. Damen
Institutions
- Fujian Medical University (CN)
- Sun Yat-sen University (CN)
- Keck Hospital of USC (US)
- University of Illinois Chicago (US)
- University of Illinois Hospital & Health Sciences System (US)
- Sun Yat-sen University Cancer Center (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Magnetic Resonance Imaging
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1016/j.mri.2024.110294
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Institutes of Health
- Basic and Applied Basic Research Foundation of Guangdong Province
- National Cancer Institute
- National Institute of Diabetes and Digestive and Kidney Diseases