Esophageal submucosal gland duct adenoma: An unrecognised esophageal counterpart of minor salivary gland tumours with frequent <i>BRAF V600E</i> mutations

This study delineates a distinct subtype of benign adenoma arising from the esophageal submucosal gland duct, characterised by multiple lobulated cystic proliferation of benign epithelial layers within the submucosa. BRAF V600E mutations were present, similar to in sialadenoma papilliferum. We determined the genetic mutation present in esophageal submucosal gland duct adenoma, providing further evidence that it is an esophageal counterpart of minor salivary gland tumours.

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Publication Details

Journal
Histopathology
Published
2024-12-04
DOI
https://doi.org/10.1111/his.15384
Citations
3
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.72
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article

Esophageal submucosal gland duct adenoma: An unrecognised esophageal counterpart of minor salivary gland tumours with frequent BRAF V600E mutations

Ying Ding, Hongjin Hua, Hai Li, Die Hu
3 citations
Histopathology
Salivary Gland Tumors Diagnosis and Treatment
1.72
article

Esophageal submucosal gland duct adenoma: An unrecognised esophageal counterpart of minor salivary gland tumours with frequent BRAF V600E mutations

Ying Ding, Hongjin Hua, Hai Li, Die Hu
article en
3 citations

Abstract

This study delineates a distinct subtype of benign adenoma arising from the esophageal submucosal gland duct, characterised by multiple lobulated cystic proliferation of benign epithelial layers within the submucosa. BRAF V600E mutations were present, similar to in sialadenoma papilliferum. We determined the genetic mutation present in esophageal submucosal gland duct adenoma, providing further evidence that it is an esophageal counterpart of minor salivary gland tumours.

HistopathologyVol. 86(5)
Jiangsu Province Hospital (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 14%
Salivary Gland Tumors Diagnosis and Treatment
1.72
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