Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients

As suggested by WHO-HAEM5, immunoglobulin phenotype assessment (IgM alongside IgD) appears to be a possible valuable tool in the initial diagnosis of PCMZL to differentiate between the indolent class-switched PCMZL (IgM-negative) and IgM+ (IgD-) PCMZL, which has an uncertain prognosis. The variation in B-cell rearrangements and light chain restriction observed in distant recurrences of PCMZL may suggest different antigen-driven stimulation processes.

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Publication Details

Journal
Histopathology
Published
2024-12-04
DOI
https://doi.org/10.1111/his.15377
Citations
9
Primary Topic
Cutaneous lymphoproliferative disorders research
Type
article
Field-Weighted Citation Impact
4.81
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article

Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients

Charline Caumont, Adèle de Masson, Audrey Bidet, M. Beylot‐Barry et al.
9 citations
Histopathology
Cutaneous lymphoproliferative disorders research
4.81
article

Recurrent primary cutaneous marginal zone lymphoma: a comparative study of initial tumours, recurrences, and outcomes in 61 patients

Charline Caumont, Adèle de Masson, Audrey Bidet, M. Beylot‐Barry, Laurence Lamant, B. Vergier, S. Boulinguez, Pierre Dubus, Marie Donzel, G. Jeudy, Sabine Schneider, Florent Grange, Marie‐Hélène Lorton, Stéphane Dalle, Maxime Battistella, C. Ram‐Wolff, Nicolás Ortonne, Samuel Amintas, Anne Pham‐Ledard, Fanny Beltzung, Rémi Vergara, Jean‐Michel Cayuela, Nathalie Franck, B. Balme, A. Carlotti
article en
9 citations

Abstract

As suggested by WHO-HAEM5, immunoglobulin phenotype assessment (IgM alongside IgD) appears to be a possible valuable tool in the initial diagnosis of PCMZL to differentiate between the indolent class-switched PCMZL (IgM-negative) and IgM+ (IgD-) PCMZL, which has an uncertain prognosis. The variation in B-cell rearrangements and light chain restriction observed in distant recurrences of PCMZL may suggest different antigen-driven stimulation processes.

HistopathologyVol. 86(5)
Université de Bordeaux (FR), Inserm (FR), Université Paris-Est Créteil (FR), Université Paris Cité (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Centre Hospitalier Universitaire de Toulouse (FR), Hospices Civils de Lyon (FR), Bordeaux Population Health (FR), CHU Dijon Bourgogne (FR), Centre Hospitalier de Valence (FR), Hôpital Saint-Louis (FR), Lymphoma Study Association (FR), Institut Alfred Fournier (FR), HIPI - Immunologie humaine, physiopathologie et immunithérapie (FR), BoRdeaux Institute of onCology (FR)
Openalex Percentile: Top 5%
Cutaneous lymphoproliferative disorders research
4.81
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