Alterations in DNA Damage Repair Genes Before and After Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer
Patients with muscle-invasive bladder cancer who have mutations in genes that are involved in repair of DNA damage are more likely to respond to cisplatin-based chemotherapy. Testing to identify these gene mutations could help in selecting the patients who are most likely to benefit from this treatment.
Authors
- Ursula Lemberger (ORCID: https://orcid.org/0000-0003-2019-6111)
- Ekaterina Laukhtina
- Andreas Bruchbacher (ORCID: https://orcid.org/0000-0001-9034-3928)
- Sigurd Krieger
- Bernhard Englinger (ORCID: https://orcid.org/0000-0002-9701-2600)
- Büsra Ernhofer (ORCID: https://orcid.org/0009-0008-2409-6402)
- Éva Compérat (ORCID: https://orcid.org/0000-0001-8488-543X)
- Melanie R. Hassler (ORCID: https://orcid.org/0000-0002-9496-4411)
- André Oszwald (ORCID: https://orcid.org/0000-0002-8298-6381)
- Shahrokh F. Shariat
- Andrea Haitl
Institutions
- Al-Ahliyya Amman University (JO)
- Cornell University (US)
- Charles University (CZ)
- Comprehensive Cancer Center Vienna (AT)
- Medical University of Vienna (AT)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- European Urology Open Science
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1016/j.euros.2024.10.022
- Citations
- 5
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.86