Protein‐coding mutation in <scp><i>Adcy3</i></scp> increases adiposity and alters emotional behaviors sex‐dependently in rats
The ADCY3 TM domain plays a role in protein function via p-AMPK and CREB signaling. Adcy3 may contribute to the relationship between obesity and major depressive disorder, and sex influences the relationships between Adcy3, metabolism, and behavior.
Authors
- C. Ronald Scott
- Leah C. Solberg Woods (ORCID: https://orcid.org/0000-0002-7943-798X)
- M.L. Fitzpatrick (ORCID: https://orcid.org/0000-0003-0107-0169)
- Angela Beeson (ORCID: https://orcid.org/0000-0002-4388-5983)
- Michael N. Grzybowski (ORCID: https://orcid.org/0000-0002-8115-2748)
- Aron M. Geurts (ORCID: https://orcid.org/0000-0002-4347-2505)
- Alexandria Szalanczy (ORCID: https://orcid.org/0000-0002-2386-0164)
- Jason Klotz
- Anusha Vora
- Nataley Der
- Rong Chen
Institutions
- Medical College of Wisconsin (US)
- Wake Forest University (US)
Publication Details
- Journal
- Obesity
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1002/oby.24178
- Citations
- 2
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Wake Forest University
- National Institute on Alcohol Abuse and Alcoholism
- National Institute on Drug Abuse
- National Institute of Diabetes and Digestive and Kidney Diseases