The Importance of Stem Cells in the Treatment of Neuropathic Pain

Many disorders, including heart, bone, cancer, liver, and brain disease, have been treated using stem cell therapy as a viable alternative. The somatosensory system is affected by a lesion, which leads to neuropathic pain (NP), and just a relatively tiny fraction of patients now receive effective care from existing pharmacological medications. There have been studies to show the effectiveness of various stem cells in reducing or treating experimental neurological pain, although these studies are uncommon in number. In this review, we will summarize the preclinical and clinical research that has been conducted on the effectiveness of several stem cell types, such as mesenchymal stem cells, bone-derived stem cells, and neural stem cells, in reducing neurological pain in this study.

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Publication Details

Journal
Central Nervous System Agents in Medicinal Chemistry
Published
2024-12-04
DOI
https://doi.org/10.2174/0118715249328823241111101137
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The Importance of Stem Cells in the Treatment of Neuropathic Pain

Saeed Gharooee Ahangar, Siavash Beiranvand, Tayebeh Khosravi, Farshad Hassanzadeh Kiabi
Central Nervous System Agents in Medicinal Chemistry
Pain Mechanisms and Treatments
article

The Importance of Stem Cells in the Treatment of Neuropathic Pain

Saeed Gharooee Ahangar, Siavash Beiranvand, Tayebeh Khosravi, Farshad Hassanzadeh Kiabi
article en

Abstract

Many disorders, including heart, bone, cancer, liver, and brain disease, have been treated using stem cell therapy as a viable alternative. The somatosensory system is affected by a lesion, which leads to neuropathic pain (NP), and just a relatively tiny fraction of patients now receive effective care from existing pharmacological medications. There have been studies to show the effectiveness of various stem cells in reducing or treating experimental neurological pain, although these studies are uncommon in number. In this review, we will summarize the preclinical and clinical research that has been conducted on the effectiveness of several stem cell types, such as mesenchymal stem cells, bone-derived stem cells, and neural stem cells, in reducing neurological pain in this study.

Central Nervous System Agents in Medicinal ChemistryVol. 25(4)
Isfahan University of Medical Sciences (IR), Lorestan University of Medical Sciences (IR), Kermanshah University of Medical Sciences (IR), Mazandaran University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 69%
Pain Mechanisms and Treatments
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