Muscle tissue transcriptome of F1 Angus-Nellore bulls and steers feedlot finished: impacts on intramuscular fat deposition
The current findings suggest the importance of these pathways and genes for lipid metabolism in steers with greater IMF. Notably, this study reveals for the first time the involvement of the PI3K-Akt pathway and associated genes in regulating IMF deposition in F1 Angus-Nellore cattle. Castration influenced DEGs linked to energy metabolism and lipid biosynthesis, highlighting key molecular players responsible for IMF accumulation post-castration in beef cattle.
Authors
- Pedro H V Carvalho (ORCID: https://orcid.org/0000-0003-1620-6831)
- Luis Artur Loyola Chardulo (ORCID: https://orcid.org/0000-0003-2656-1562)
- Guilherme Luís Pereira (ORCID: https://orcid.org/0000-0002-0400-0142)
- Germán Darío Ramírez-Zamudio (ORCID: https://orcid.org/0000-0002-4843-7653)
- Irene Alexandre Reis (ORCID: https://orcid.org/0000-0001-7821-1877)
- Welder Angelo Baldassini (ORCID: https://orcid.org/0000-0003-0840-2082)
- Marcos Roberto Chiaratti (ORCID: https://orcid.org/0000-0001-8805-9469)
- Otávio Rodrigues Machado Neto (ORCID: https://orcid.org/0000-0002-4449-7771)
- Rogério Abdallah Curi (ORCID: https://orcid.org/0000-0001-6289-0406)
- Iasmin Myrele Santos Calaça de Farias (ORCID: https://orcid.org/0000-0001-6605-3824)
- Ricardo Perecin Nociti (ORCID: https://orcid.org/0000-0002-0831-5264)
- Sérgio A G Pereira-Junior (ORCID: https://orcid.org/0000-0003-3748-5091)
Institutions
- Universidade Federal de São Carlos (BR)
- Universidade de São Paulo (BR)
- Universidade Estadual Paulista (Unesp) (BR)
- Colorado State University (US)
Publication Details
- Journal
- BMC Genomics
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1186/s12864-024-11066-8
- Citations
- 6
- Primary Topic
- Meat and Animal Product Quality
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior