Gut Microbiota and Athletes’ Health

Purpose: A synthesis of world literature on actual knowledge of intestine microbiota influence on athletes’ health. Methods and materials: National and foreign literature on actual knowledge of intestine microbiota influence on athletes’ health was analyzed. MEDLINE, Embase, Scopus, Web of Science, eLIBRARY, PubMed data Google Academy data bases were used for searching the literature for the period from 2012 to 2024. The following key words and their combinations were applied for search: “athletes”, “gut microbiota “, “butyrate”. Results: A microbiota is a key factor of human organism homeostasis maintenance. It provides next functions: energy metabolism, maturation and maintenance of immune system, synthesis of vitamins, regulation of bile acids reabsorption in intestine and lots of other functions. Furthermore, bacteria produce some human hormones analogues: serotonin, histamine, dopamine, norepinephrine, testosterone. According to the recent information, intestine microbiota modification could provide a beneficial influence on human organism that cause a sport results improvement. Modulation of immune response, oxidative stress, metabolic processes and nutrients bioavailability is a general mechanism of microbiota influence on training adaptation. Microbiome affects the muscular protein synthesis, biogenesis and function of mitochondria and the muscular glycogen accumulation. Conclusion: Currently there is a necessity of further investigations of “microbiome-muscles” relationship.